November 22, 2008
| Bio-IT World

Top Headlines

Geospiza Builds Tool Kit with GeneSifter
| TechFlash | Geospiza, the Seattle genetic analysis software company, is expanding its product line. more
Sequenom Plans to Expand SNP Testing Opportunity
| Boston Globe | Sequenom’s best-known product is designed to test for Down syndrome, but the genetic testing products company said Tuesday that there may be an even larger market is other kinds of prenatal testing. more
Woolly Mammoth Genome Partially Sequenced
| The Times/AFP | Scientists said they had reconstructed around half of the genome of the woolly mammoth, a species that became extinct at the end of the last Ice Age some 11,000 years ago. more

MORE NEWS BELOW

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Targeted Therapies Are the Future - Lilly Chairman
| Arizona Republic | The chairman of Eli Lilly & Co. said the future of the pharmaceutical industry rests not with blockbuster drugs but with targeted therapies that work for smaller groups of people based on their biological makeup. more
Doctors Transplant Windpipe with Stem Cells
| Yahoo!/AP | Doctors have given a woman a new windpipe with tissue grown from her own stem cells, eliminating the need for anti-rejection drugs. more
Stem Cells Restore Hearing, Vision in Animals
| Reuters | Stem cells from tiny embryos can be used to restore lost hearing and vision in animals, researchers said on Tuesday in what they believe is a first step toward helping people. more

White Papers & Special Reports

Waters white paper image
Software Helps Doping Control Lab Streamline Results Management
Sponsored by Waters
The Karolinska University Hospital’s Doping Control Lab tests thousands of samples annually for stimulants, diuretics, and other masking agents. Increased regulatory pressure and new technologies increased the number of samples analyzed creating data management challenges. Waters® NuGenesis® Scientific Data Management System and TargetLynx™ Application Manager software were used to reduce the time required to calculate, review and search results.
sas whitepaper92
Managed Innovation, Assured Compliance
Sponsored by SAS
Discovery organizations are identifying a lot of promising compounds, but clinical research processes haven't kept pace with timely testing of all those potential therapies. This white paper describes how SAS® Drug Development supports true innovation across the clinical trial process.

In this white paper you will learn how to:

  • Assemble data to foster better collaboration
  • Get up-to-date information during clinical trials
  • Make informed decisions earlier in the trial process
BlueArc white paper image
Addressing Life Sciences Constantly Growing Data Challenges Research Environments
Sponsored by BlueArc
The continued explosion of raw experimental data, the increased use of video, the growing adoption of new data retention practices, and the move to high throughput computational workflows are all placing new demands on the way life sciences organizations store and manage their data.

Download this white paper to learn about:

  • Factors driving the data explosion in the life sciences
  • New data management issues that must be addressed
  • HPC trends that are placing new demands on storage
  • Storage solution attributes that address performance, manageability, and energy efficiency.


Expert Comment

Practical Considerations in Adaptive Clinical Trial Implementation

By Bill Byrom and Graham Nicholls
ClinPhone

Aug. 18, 2008 |  Adaptive clinical trials use the analysis of accumulating subject data to make changes to the study without undermining its inherent validity or integrity.  

Such designs bring with them new implementation challenges: rapid access and cleaning of response data, seamless execution of randomization changes and ensuring sufficient supplies are at site following a randomization change. Read more.

Bio-IT World encourages readers to share their opinions on issues of interest to the life sciences community. To submit a commentary for consideration, contact Kevin Davies.

Life Science Webcasts & Podcasts

Medidata Solutions

Rising Clinical Trial Delays and Costs - Addressing the Cause, Not the Symptoms 

medidata podcastProtocol complexity is taking a toll on clinical study speed and efficiency: increasingly complicated and ambitious protocols are not only burdening sites and study volunteers but are also prolonging trials and increasing expenses. In response, sponsors have turned to global study placement, restructured site relationships and new site management practices, but the problem remains.

This podcast will discuss:

  • Why these responses address only the symptoms, not the underlying cause, of rising clinical trial delays and costs.
  • Results of a recent joint Tufts University / Medidata Solutions study.
  • New metrics benchmarking protocol design trends.
  • Systematic protocol design improvements and why they are essential to clinical trial performance excellence.

Speakers: Ken Getz, Senior Research Fellow at the Tufts Center for the Study of Drug Development, and Ed Seguine, General Manager, Trial Planning Solutions at Medidata.

Download Now 



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Bio-IT Briefs

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Job Openings

Director, Center For Information Technology (CIT) - National Institutes of Health  (NIH), Department of Health and Human Service
Located in Bethesda, MD. This position requires:
• High-level vision, leadership, management, and modernization of CIT programs and services.
• Strategic direction and policy development for CIT long-term operations and objectives.
• Serve as a key IT advisor to the NIH Chief Information Officer.
A TOP SECRET security clearance will be required.  More job detail is found at:  http://www.jobs.nih.gov under the Executive Jobs section.Or contact Ms.Winnie Garner at seniorre@od.nih.gov.  Applications must be received ELECTRONICALLY by (11:59 p.m.), December 17, 2008.  DHHS and NIH are Equal Opportunity Employers

Bioinformatics Manager- Lilly Singapore Centre for Drug Discovery
For more information click here 

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