OmniComm Systems, Inc. And City Of Hope Collaboration To Benefit Entire Cancer Research Community

EDC Company to collaborate with leading Cancer Center to build standards-based eCRFs and make available outcome of collaboration to other users.

FT. LAUDERDALE, FL - December 4, 2007 - /MarketWire/ - OmniComm Systems, Inc. (OTC Bulletin Board: OMCM.OB), a leader in integrated electronic data capture (EDC) solutions for clinical trials, today announced that City of Hope (a recent license customer of the TrialMaster® product suite) and OmniComm are working together to develop a set of caDSR derived standardized case report forms and reporting tools to support National Cancer Institute (NCI) reporting requirements. These reusable forms and tools will be made freely available to other Cancer Centers by OmniComm and City of Hope following a formal process of user acceptance testing led by City of Hope staff. City of Hope intends to use these standardized forms and NCI reporting tools for the first trial that they put into production using their TrialMaster environment.

"OmniComm is employing our extensive experience in building eCRFs to build a library of eCRFs based on standards extracted from the caDSR and have already completed the initial build of all the forms used to meet the reporting requirements for many NCI funded trials," said Stephen Johnson, Executive Vice President of Business Development, Professional Services and Client Services and Support at OmniComm. "We are confident that working with City of Hope to validate the results and optimize the resulting eCRFs will produce a high quality reusable tool that many of our clients will benefit from."

"We plan to use this library as the foundation for data collection in our early-phase oncology trials," said Jeffrey Longmate, Ph.D., Director of Biostatistics at City of Hope. "Having a broad collection of standard data elements already mapped to meet our typical research needs and major reporting requirements will help us rapidly launch new protocol-specific eCRFs implemented with TrialMaster. We hope that the savings in time and effort will broaden the feasibility of electronic data capture in the Cancer Center environment."

The plan to make this library of standards-based eCRFs and associated reporting tools available to other Cancer Centers is consistent with other City of Hope informatics contributions to the community including its on-going caBIG related activities. Similarly, making these tools available to users of TrialMaster is consistent with OmniComm's commitment to ensuring the availability of high quality and reusable tools for its customers. The pledge to make this resource freely available to future adopters of TrialMaster will further reduce the time required to bring NCI funded trials live.

About OmniComm
OmniComm Systems, Inc. (www.OmniComm.com) provides customer-driven Internet solutions to pharmaceutical, biotechnology, research and medical device organizations that conduct life changing clinical trial research. OmniComm's growing base of satisfied customers is a direct result of the company's commitment to deliver products and services that ensure ease of use, faster study build, ease of integration and better performance. OmniComm's client intuitive pricing model allows companies that range from small to mid-size to large scale institutions to safely and efficiently capitalize on their clinical research investments.

OmniComm ranked in the top 150 as one of the fastest revenue growth technology companies in North America during the last 5 years. OmniComm Systems Inc. has corporate headquarters in Ft. Lauderdale, Florida with offices in Bonn, Germany, Tula, Russia, California, Maryland, New York, North Carolina and Texas.

About City of Hope
City of Hope is a leading research and treatment center for cancer, diabetes and other life-threatening diseases. Designated as a Comprehensive Cancer Center, the highest honor bestowed by the National Cancer Institute, and a founding member of the National Comprehensive Cancer Network, City of Hope's research and treatment protocols advance care throughout the nation. City of Hope is located in Duarte, California, just northeast of Los Angeles, and is ranked as one of "America's Best Hospitals" in cancer and urology by U.S.News & World Report. Founded in 1913, City of Hope is a pioneer in the fields of bone marrow transplantation and genetics. For more information, visit www.cityofhope.org.

Safe Harbor Disclaimer
Statements about OmniComm's future expectations, including without limitation, future revenues and earnings, plans and objectives for the future operations, future agreements, future economic performance, operations and all other statements in this press release other than historical facts are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934, and as that term is defined in the Private Securities Litigation Reform Act of 1995. OmniComm intends that such forward-looking statements be subject to the Safe Harbors created thereby. Since these statements involve risks and uncertainties, including but not limited to economic competitive, governmental, contractual and technological factors affecting OmniComm's operations, markets and profitability, actual results could differ materially and adversely from the expected results.

PRESS RELEASE
for Immediate Release
Lizanne Kelley
OmniComm Systems, Inc.
954-473-1254 Extension 283
lkelley@omnicomm.com

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